Laboratory parameters – Communicable Diseases Research

What are the long-term holistic health consequences of COVID-19 among survivors? An umbrella systematic review

Article

Published on 2022-12-012022-11-16
Journal: Journal of medical virology
[Category] COVID19(2023년), SARS, 변종,

Immunogenicity and safety of BNT162b2 mRNA vaccine in Chinese adults: A phase 2 randomised clinical trial

Article

Published on 2022-12-012022-10-06
Journal: The Lancet Regional Health - Western Pacific
[Category] 진단,

[키워드] acute respiratory syndrome Administered Adults adverse event AEs age analysis assessment assigned BNT162b2 BNT162b2 mRNA BNT162b2 mRNA vaccine China Chinese clinical trial Complete Completed conducted coronavirus COVID-19 development dose double-blind Efficacy and safety enrolled Follow-up geometric mean titer GMT GMTs Han Chinese healthy immune response immunogenicity immunogenicity endpoint Inc independent individual injection intramuscular Intramuscular injection investigators Laboratory parameters management messenger Messenger RNA Mild moderate mRNA vaccine Neutralising Antibodies neutralising antibody of BNT162b2 participant Participants pharmaceutical Placebo placebo-controlled trial randomisation randomised Randomly reactogenicity receive recipients recruited reduced remained reported resolved Result robust Safety SARS-CoV-2 SARS-CoV-2 variant SCR second dose sera serious AE seroconversion rate severity Shanghai Sponsor statisticians stratified T-cell Response the placebo group Tolerability Treatment Trial utilised vaccination vaccination. vaccine administration were blinded
[DOI] 10.1016/j.lanwpc.2022.100586 PMC 바로가기 [Article Type] Article

Vitamin D deficiency is Associated with Increased Risk of Delirium and Mortality among Critically Ill, Elderly Covid-19 Patients

Research article

Published on 2022-11-012022-10-05
Journal: Complementary therapies in medicine
[Category] COVID19(2023년), SARS, 바이오마커,

[키워드] adjusted association baseline blood pressure collected data Comorbidities confounders coronavirus disease COVID-19 COVID-19 mortality COVID-19 patients Critically ill deficiency delirium demographic characteristics elderly Elderly patient Face mask higher risk Hospital admission Hospitalization Hospitalized ICU ICU admission Ill IMV incidence increase in Increased increased risk information intensive care Invasive mechanical ventilation Laboratory parameters less lower risk mechanical ventilation medications Mortality Older Organ failure outcome Patient positive prevalent propofol Prospective Study Result risk SARS-CoV-2 serum single center Study participants Treatment Vitamin D vitamin D deficiency vitamin D level vitamin D sufficiency was done were recorded
[DOI] 10.1016/j.ctim.2022.102855 [Article Type] Research article

Distinct Immune Phenotypes and Cytokine Profiles in Children with Differing Severity of COVID-19

Article

Published on 2022-11-012022-11-15
Journal: The Pediatric Infectious Disease Journal
[Category] SARS, 진단, 치료기술,

[키워드] Absolute lymphocyte count activated acute phase acute respiratory syndrome Anti-inflammatory Antibody Response CD3 CD4 CD8 Cell children children with COVID-19 Clinical outcome clinical presentation coronavirus Coronavirus disease 2019 COVID-19 COVID-19 patients cytokine profile decrease dependent on disease severity distress effector memory exhibited groups help HLADR IL-1ra IL-1β immune mechanism Immune phenotype Immune profile increase in Infection Inflammatory Laboratory parameters Mild MIS-C no difference not significantly different Patient pediatric profile prospective cohort study RANTES SARS-CoV-2 IgG SARS-CoV2 sera severe disease severity syndrome T cell T cells tumor necrosis factor-α was performed with COVID-19
[DOI] 10.1097/INF.0000000000003669 PMC 바로가기

DNA damage in peripheral blood lymphocytes of severely ill COVID-19 patients in relation to inflammatory markers and parameters of hemostasis

Article

Published on 2022-10-262022-11-15
Journal: Mutagenesis
[Category] 바이오마커, 치료제,

[키워드] activated Analysis Antibiotics Anticoagulant antiviral therapy applied Bearing biochemical C-reactive protein (CRP Chest chest X-ray Concentration contribute control subjects Corticosteroid COVID-19 COVID-19 patient COVID-19 patients demonstrated DNA DNA damage female Female patients Genetic Genome genotoxic healthy control healthy controls hematological parameters Hemostasis hemostasis abnormalities hospitalized COVID-19 patient IL-6 indicated Inflammation Inflammation. Inflammatory marker Laboratory laboratory parameter Laboratory parameters leukocyte lymphocyte neutrophil parameter performed peripheral blood lymphocyte Platelet positive positive correlation positively correlated procalcitonin reagent shown significantly significantly higher smoking statistically study population subjects therapy variety viral infections was measured X ray
[DOI] 10.1093/mutage/geac011 PMC 바로가기

Evaluation of the efficacy of oral nano-silymarin formulation in hospitalized patients with COVID-19: A double-blind placebo-controlled clinical trial

Article

Published on 2022-10-012022-11-15
Journal: Phytotherapy research : PTR
[Category] COVID19(2023년), SARS, 치료제,

[키워드] alanine aminotransferase Anti-viral Antiviral assigned baseline clinical trial Concomitant COVID-19 cytokine release Cytokine release syndrome Dexamethasone dosage double-blind Effect effective Effectiveness Efficacy Evidence follow-up period gel Hospitalization hospitalized patient Laboratory Laboratory parameters lack liver enzyme management outbreak pandemic participant Patient patients with COVID-19 placebo group placebo-controlled clinical trial receiving Remdesivir sample sizes SARS-CoV-2 significant difference significantly silymarin. Symptom the placebo group therapeutic strategy Treatment treatment group two group viral disease were assessed
[DOI] 10.1002/ptr.7537 PMC 바로가기

The prognostic value of biomarker levels and chest imaging in patients with COVID-19 presenting to the emergency department

응급실에 제출하는 COVID-19 환자의 바이오마커 수치 및 흉부 영상의 예후 가치

Article

Published on 2022-09-012022-09-11
Journal: The American journal of emergency medicine
[Category] COVID19(2023년), MERS, SARS, 바이오마커,

[키워드] 95% CI age AUC Biomarker Biomarkers C-reactive protein Care Chain Reaction Chest CT chest imaging COVID-19 COVID-19 patient COVID-19 patients CRP D-dimer Department dimer Emergency emergency department ferritin Hospital mortality ICU admission in-hospital mortality Laboratory parameters Lactate lactate dehydrogenase LDH Logistic regression Lung imaging lymphocyte mechanical ventilation Mortality Natriuretic neutrophil Neutrophil to lymphocyte ratio. neutrophil/lymphocyte ratio NLR not performed obesity Patient patients with COVID-19 peptide performed polymerase chain polymerase chain reaction positive presenting Primary outcome procalcitonin prognostic Prognostic value Quantitative real-time reverse transcriptase retrospective reverse transcriptase Reverse transcriptase polymerase chain reaction severity significantly tested troponin vital sign
[DOI] 10.1016/j.ajem.2022.06.043 PMC 바로가기 [Article Type] Article

Characteristics and predictors of outcomes of critically Ill children with SARS-CoV-2 infection – the PICU experience

Article

Published on 2022-09-012022-11-15
Journal: Jornal de pediatria
[Category] SARS, 진단,

[키워드] Administered Admission age Care children Clinical characteristics Comorbidity COVID COVID-19 Critically ill Critically ill children CRP D-dimer demographic died discharged distress elevated Factor Fever hospital Hospitalized ICU Ill Infant Infants infected children inflammatory markers intensive care Intervention IVIG Laboratory parameters Lactate less majority mechanical ventilation MIS-C mortality rate Older outcome outcomes Patient patients pediatric performed PICU predictor Predictors of unfavorable outcome. procalcitonin prospective observational study required SARS-CoV-2 SARS-COV-2 infection severe COVID-19 patients Shock steroid subjects Support the patient Treatment ventilator were recorded
[DOI] 10.1016/j.jped.2021.12.006 PMC 바로가기

Inflammatory and thrombotic parameters associated with the COVID-19 course in Poland (SARSTer study)

Article

Published on 2022-09-012022-11-15
Journal: Advances in medical sciences
[Category] 바이오마커,

[키워드] analyzed Anticoagulants C-reactive protein clinical Clinical improvement Coagulation Concentration Course COVID-19 CRP D-dimer database Dexamethasone diagnosed with COVID-19 epidemiologist examined ferritin group IL-6 Inflammatory marker interleukin-6 Laboratory parameters Logistic regression Lymphocyte count material Mild multivariate National neutrophil neutrophil count neutrophil. not differ outcome parameter parameters Patient patients Platelet Poland predictor procalcitonin Remdesivir selected Significant significant difference significantly significantly higher study population supported the disease thrombotic Tocilizumab Treatment WBCs White blood cell
[DOI] 10.1016/j.advms.2022.07.003 PMC 바로가기

Persistence, prevalence, and polymorphism of sequelae after COVID-19 in unvaccinated, young adults of the Swiss Armed Forces: a longitudinal, cohort study (LoCoMo)

Research article

Published on 2022-08-262022-10-05
Journal: The Lancet. Infectious Diseases
[Category] COVID19(2023년), SARS, 진단,

[키워드] Administered Adults aerobic age asymptomatic infection base Blood BMI cardiovascular complications cholesterol cohort study Concentration control group COVID-19 COVID-19 group criteria defined Diagnosis diagnostic dyslipidaemia enrolled fatigue Fatigue scale female finding Follow-up force funding Health healthy higher risk individual Intensive IQR Laboratory Laboratory parameters LDL longitudinal cohort study male management median men metabolic disorder negative RT-PCR neurological no symptoms non-hospitalised organ systems outcomes participant Participants persistent physical polymorphism positive positive PCR test presenting Prevalence Psychological public health quantified questionnaire Registered renal reported reproductive RT-PCR test SARS-CoV-2 SARS-COV-2 infection Serologically serologically positive significant difference study groups Switzerland Symptom the median threshold were excluded with COVID-19
[DOI] 10.1016/S1473-3099(22)00449-2 [Article Type] Research article